Two sample MR report
RRP7A_Dendritic Cell (DC) against finn-b-ASTHMA_ALLERG_EXMORE
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 7 | 0.6882794 | 0.4841585 | 0.2144028 |
| Weighted median | 7 | -0.1002636 | 0.0295948 | 0.0007043 |
| Inverse variance weighted | 7 | -0.0736157 | 0.0329969 | 0.0256821 |
| Simple mode | 7 | -0.0990864 | 0.0345243 | 0.0284254 |
| Weighted mode | 7 | -0.0990864 | 0.0340204 | 0.0268906 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 9.480805 | 5 | 0.0913561 |
| Inverse variance weighted | 14.193947 | 6 | 0.0275431 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.5209293 | 0.3304161 | 0.175715 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 6.3e-05 | 0 | TRUE | 0.4552958 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
